I agree humans do have their own biological limitations. Some have limitation in academics, others in job/business or personal traits. But everyone can do one thing in common: Doing the best!
Though you must strive to give every ounce of your energy, blood & sweat in your health, wealth, job, business, relationship, study, career, etc.
Even if you fail after trying your best, you’ll be satisfied for the efforts you put in. Chances are bleak that you’ll regret failing because you know that you did whatever you could in your control. For things not in your control, no point in regretting. And believe me, life without regrets is worth living.
Whatever you do, do your best.
Do the best and god will do the rest.